This piece shows everything you need on Chiefs vs Chargers. On Thursday Night, the Kansas City Chiefs will open the second week of the season against the Los Angeles Chargers. For those who are unaware, the first Amazon Prime Video game will launch on Thursday.
Only those with an Amazon Prime membership may watch the game. Anyway, the Chargers defeated the Las Vegas Raiders by a score of 24-19 last week. They’ve already won their division handily.
The Chiefs defeated the Arizona Cardinals 44-21, demonstrating that they are still a Super Bowl contender. Tyreek Hill perhaps wasn’t necessary for the Chiefs after all.
But after only one week of football, we won’t get ahead of ourselves. Here are our choices, forecasts, and odds for the Los Angeles Chargers vs. Kansas City Chiefs game on Thursday.
Match Overview: Chiefs vs Chargers
- Date: September 15, 2022
- Game Time: 8:15 PM ET
- Where to Watch: Amazon Prime Video
Odds To Remember: Chiefs vs Chargers
- Spread: Chiefs -3.5 (+100)
- Total Odds: Over 54.5 (-105)
- Moneyline Odds: Chiefs (-170)
Injury Report: Chargers
Questionable: WR Justin Watson (Chest), CB Trent McDuffie (Hamstring), G Trey Smith (Ankle)
Injury Report: Chiefs
Questionable: WR Keenan Allen (Hamstring), CB J.C. Jackson (Ankle)
Our Prediction: Kansas City Chiefs vs Los Angeles Chargers
In their first game of the season, the Kansas City Chiefs looked fantastic. The Kansas City Chiefs completely outplayed the Arizona Cardinals in every facet of the game.
On 30-of-39 passing attempts, Patrick Mahomes passed for 360 yards and five touchdowns. He made two early Clyde-Edwards Helaire connections and kept Travis Kelce and JuJu Smith-Schuster active in the game.
Isiah Pacheco received more touches, carrying 12 times for 62 yards and a score of his own despite Edwards Helaire receiving the start and scoring two touchdowns as running back.
Strong Defense Limited The Cardinals’ Offense To 282 Yards
The Cardinals’ attack, on the other hand, was limited to only 282 yards as a direct result of the efforts of the defense. It was anticipated that the Cardinals would have the most powerful and lightning-quick offense in the league.
They were barely successful in 18 of their 42 offensive plays, and their total yardage was just 282. The Cardinals were able to score both of their touchdowns in the last few minutes of the game, despite Kyler Murray only throwing for 179 yards for the Cardinals.
In the meanwhile, the Chargers were victorious in a nail-biting contest against the Raiders at home. In the game that they won, Justin Herbert passed for three touchdowns while only throwing one interception.
The running game, on the other hand, did not make a very good impression on Los Angeles. Although he only had 36 yards on the ground, Austin Ekeler led the Chargers in running with 14 touches (averaging 2.5 ypc).

Chargers’ Poor Run Game Blocking Certainly Wasn’t Helpful
In the end, it didn’t matter since the Chargers’ run defense was poor. But against the Raiders, the pass protection was improved, as six different guys caught three or more passes from Herbert.
Keenan Allen’s injury, though, was the main story of Week 1. Due to a hamstring injury, he could be out for a while. He may or may not be able to participate. If he is unable to play, his absence will be felt.
Before being hurt, he caught four of four targets for a total of 66 yards. Without the injury, he would have had a far more productive day. On the other side, the Chargers run defense was dreadful.
Despite only having 13 attempts, the Raiders gained 4.9 yards per carrying. Last week against the Cardinals, the Chiefs ran the ball 27 times, but that was only possible because they had such a large lead early on.
The Chiefs Would Rather Toss The Ball Than Hurry It
More than rushing it, the Chiefs like to toss it. The Chargers, on the other hand, had a strong game plan for rushing the passer against the Raiders and ought to give Mahomes some competition.
I think the Chiefs will win if they can quickly establish their run game. The Chargers just don’t have another high-volume catcher who can step in for Keenan Allen if he becomes injured and is unable to play.
I shall thus cheer for the Chiefs at home in this game. I predict a shootout as well, but once again, if Allen is out, I won’t be supporting the Chargers since I know his use may be reduced this year.