NFL action begins on Thursday with a matchup between the Buffalo Bills and the Los Angeles Rams. Who will emerge victorious from this competition?
Check out these choices and predictions for the game that will be broadcast on NBC at 5:20 p.m. Mountain Standard Time during NFL Week 1. The Bills are now favored by 2.5 points to win the game.
Rams win, 30–27, According to CBS Sports
Throughout the course of the season, it is probable that both of these teams will be regarded as favorites to win the Super Bowl due to their formidable on-field performances.
In spite of this, the defending champions seem to have a little advantage as they begin their championship defense. There appears to be a little bit of additional energy for them.
The reigning champs have a record of 18-3 straight up and 13-6-2 against the spread in Week 1 dating back to Super Bowl XXXIV.
That fact alone ought to be enough to sway people in favor of the Rams, particularly now that they are going into Year 2 with Matthew Stafford.
Bills Score 34, Rams Score 31 According to the Pro Football Network
I believe the Bills will finally break through in 2022. After suffering a crushing defeat at the hands of the Chiefs in the Divisional Round, Josh Allen, Stefon Diggs, and Devin Singletary are more motivated than ever to have a solid start to the season.

The majority of the Rams roster is intact from the club that recently won the Super Bowl. Cooper Kupp continues to be the finest wide receiver in football, and Matthew Stafford will be back for Year 2 of the season.
On the other hand, I think the Bills will be victorious away from home against the reigning champions.
Bookies.com Recommends Taking the Bills in Their Week 1 Matchup Against the Rams
The “Battle of the Seans” kicks off the new NFL season and serves as a possible preview for Super Bowl 57. In the wake of Sean Payton’s decision to step down as head coach of the New Orleans Saints, the “Sean” coaching bragging rights will be decided between Sean McVay and Sean McDermott.
The Rams are in for an increasingly difficult season. In addition to their first game of the season against the Bills, the Rams will face Dallas at home and will travel to Tampa Bay, the site of their playoff victory over the Buccaneers from the previous season.
The Rams get a reprieve in that they have the whole offseason to get ready for their matchup against the Bills, but this game has all the makings of a major disappointment for the home side in terms of its potential outcome. The Bills, as well as the point, are yours to seize.
The Bills are the Team to Back in Week 1 against the Rams, According to Walter Football
It’s possible that some journalists and other media types will be caught off guard by its proliferation. A friend of his on Facebook named Joe B. brought to our attention the fact that CBS had said that the Rams were essentially the same squad.
Well, yes, with the exception of their Pro Bowl left tackle hanging up his cleats and their Hall of Fame edge rusher signing with the exact same club that the Rams will face in Week 1. It would not surprise me if the Bills came out on top in this contest given that they are the superior team.